Role of Corticosteroids in Treatment of Vitiligo
نویسنده
چکیده
Vitiligo is the most frequent pigmentary disorder ( Bagherani et al., 2011; Nazer et al., 2011;Yaghoobi et al., 2011a; as cited in Wolff et al., 2007). It is an acquired, idiopathic and progressive skin disease (Bagherani et al., 2011; Shameer et al., 2005; Yaghoobi et al., 2011a), characterized by sharply demarcated depigmented lesions on any part of the body (Van Geel et al., 2004). This disease can also affect hair and mucosal areas such as mouth and genitalia (Gawkrodger et al., 2010).
منابع مشابه
میزان پاسخ به درمان با دوز پایین کورتیکواستروئید سیستمیک در بیماران ویتیلیگو بیمارستان رازی، 80-1379
Background: Vitiligo is an acquired pigmentary disorder that affects 1% of population. It presents as depigmented patches. One of the most probable theories regarding the pathogenesis of vitiligo is autoimmunity. Systemic corticosteroids may arrest the progression of vitiligo and lead to repigmentation by suppressing immune system. The objective of this study is to assess the clinical efficacy ...
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Background: Topical corticosteroids and oral psoralen plus ultraviolet A radiation (PUVA therapy) are two common treatment methods for vitiligo. The aim of this study was to compare the efficacy, complications and patterns of repigmentation of these two methods. Methods: This prospective randomized clinical trial was conducted from July 2007 to October 2008. Patients with disseminated vitiligo ...
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Vitiligo is an acquired disorder characterized by depigmented macules on skin, hair, and mucosa. Its prevalence worldwide is 0.1-2% and varies from country to country.1 It is associated with high psychiatric morbidity and dysfunction, particularly in darker skin types where the contrast between normal and depigmented skin is highly pronounced.2,3 The usual approach to the treatment of vitiligo ...
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Background: Vitiligo is a skin autoimmune disease that affects 0.1% to more than 8% of people in the world. About 50% of patients develop the disease before the age of 20. In this disease, melanocytes are destroyed in the skin, mucous membranes and retina. As a result, white spots appear on different parts of the body. Studies have suggested the role of oxidative stress in vitiligo. Coenzyme Q1...
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Vitiligo is an acquired cutaneous disorder of pigmentation, with an incidence of 0.5% to 2% worldwide. There are three major hypotheses for the pathogenesis of vitiligo that are not exclusive of each other: biochemical/cytotoxic, neural and autoimmune. Recent data provide strong evidence supporting an autoimmune pathogenesis of vitiligo. As vitiligo can have a major effect on quality of life, t...
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